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Camizestrant TFA

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Purity:98.9%

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COA HNMR HPLC

Camizestrant TFA

Catalog No. T11237L

Camizestrant TFA (AZD-9833 TFA) is a potent and orally active antagonist of estrogen receptor (ER).

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Pack Size	Price	Availability
1 mg	$98	In Stock
5 mg	$256	In Stock
10 mg	$379	In Stock
25 mg	$592	In Stock
50 mg	$793	In Stock
100 mg	$1,090	In Stock
500 mg	$2,190	In Stock
1 mL x 10 mM (in DMSO)	$268	In Stock

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Product Introduction

Bioactivity

Description	Camizestrant TFA (AZD-9833 TFA) is a potent and orally active antagonist of estrogen receptor (ER).
In vivo	Camizestrant TFA (oral administration; 0.2-50 mg/kg; 20 days) shows anti-tumour efficacy in human parental MCF7 mice xenograft. Camizestrant TFA (oral administration; 0.8-40 mg/kg; 30 days) decreases tumor growth. Camizestrant TFA gives almost complete tumour growth inhibition at the doses >10 mg/kg in mice[1].
Alias	Camizestrant TFA(2222844-89-3 Free base), AZD-9833 TFA

Chemical Properties

Molecular Weight	590.54
Formula	C26H29F7N6O2
Cas No.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 70 mg/mL (118.54 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6934 mL	8.4668 mL	16.9337 mL	84.6683 mL
5 mM	0.3387 mL	1.6934 mL	3.3867 mL	16.9337 mL
10 mM	0.1693 mL	0.8467 mL	1.6934 mL	8.4668 mL
20 mM	0.0847 mL	0.4233 mL	0.8467 mL	4.2334 mL
50 mM	0.0339 mL	0.1693 mL	0.3387 mL	1.6934 mL
100 mM	0.0169 mL	0.0847 mL	0.1693 mL	0.8467 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc