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Sarecycline hydrochloride
Catalog No. T21394Cas No. 1035979-44-2
Alias WC-3035, WC3035, WC 3035, Sarecycline HCl, P-005672, P005672, P 005672
Sarecycline hydrochloride (Sarecycline HCl) is an orally active narrow-spectrum tetracycline antibiotic with antimicrobial and anti-inflammatory activity, inhibits Acinetobacter and Candida tropicalis, and can be used to treat inflammatory acne.
Sarecycline hydrochloride
Catalog No. T21394Alias WC-3035, WC3035, WC 3035, Sarecycline HCl, P-005672, P005672, P 005672Cas No. 1035979-44-2
Sarecycline hydrochloride (Sarecycline HCl) is an orally active narrow-spectrum tetracycline antibiotic with antimicrobial and anti-inflammatory activity, inhibits Acinetobacter and Candida tropicalis, and can be used to treat inflammatory acne.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $147 | In Stock | |
| 5 mg | $428 | In Stock | |
| 10 mg | $623 | In Stock | |
| 25 mg | $968 | In Stock | |
| 50 mg | $1,280 | In Stock | |
| 100 mg | $1,760 | In Stock |
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Purity:99.23%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Sarecycline hydrochloride (Sarecycline HCl) is an orally active narrow-spectrum tetracycline antibiotic with antimicrobial and anti-inflammatory activity, inhibits Acinetobacter and Candida tropicalis, and can be used to treat inflammatory acne. |
| In vitro | METHODS: To evaluate the antibacterial activity of Sarecycline hydrochloride and its comparator against Cutibacterium acnes, Sarecycline hydrochloride was applied to 55 clinical isolates of Cutibacterium acnes. RESULTS: The MIC values of Sarecycline hydrochloride ranged from 0.5 to 16 μg/ml and it displayed activity against macrolide-resistant strains [1]. |
| In vivo | METHODS: To determine the in vivo efficacy of Sarecycline hydrochloride against Staphylococcus aureus RN450-1 and Escherichia coli PBS1478, a murine model of systemic (intraperitoneal) infection was utilized. RESULTS: Sarecycline hydrochloride effectively treated systemic infections caused by Staphylococcus aureus, with a protective dose at 50% (PD50) value of 0.25 mg/kg[1]. |
| Alias | WC-3035, WC3035, WC 3035, Sarecycline HCl, P-005672, P005672, P 005672 |
| Molecular Weight | 523.96 |
| Formula | C24H30ClN3O8 |
| Cas No. | 1035979-44-2 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 5 mg/mL (9.54 mM), Sonication is recommended. DMSO: 80 mg/mL (152.68 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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