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Abacavir hydroxyacetate is an orally active nucleoside analog reverse transcriptase inhibitor. It has anti-HIV and immunomodulatory activity, induces arterial thrombosis in a mouse model, and can be used to study HIV infection.
Pack Size | Price | Availability | Quantity |
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2 mg | Inquiry | In Stock |
Description | Abacavir hydroxyacetate is an orally active nucleoside analog reverse transcriptase inhibitor. It has anti-HIV and immunomodulatory activity, induces arterial thrombosis in a mouse model, and can be used to study HIV infection. |
In vivo | In 6 to 8-week-old male and female SCID mice with implantation of psoriatic tissue, Abacavir hydroxyacetate (10 and 20 mg/kg; oral gavage; 10-20 mg/kg once) decreases the concentration of PRINS and IL-20, and reduces the lesion area of the skin, showing a better effect than methotrexate in controlling psoriasis[1]. |
Alias | Abacavirhydroxyacetate |
Molecular Weight | 344.37 |
Formula | C16H20N6O3 |
Cas No. | 1446418-48-9 |
Smiles | Nc1nc(NC2CC2)c2ncn([C@@H]3C[C@H](COC(=O)CO)C=C3)c2n1 |
Relative Density. | 1.69 g/cm3 (Predicted) |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (232.31 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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