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Abacavir hydroxyacetate
Abacavir hydroxyacetate is an orally active nucleoside analog reverse transcriptase inhibitor. It has anti-HIV and immunomodulatory activity, induces arterial thrombosis in a mouse model, and can be used to study HIV infection.
Catalog No. T1267LCas No. 1446418-48-9
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Purity:98.29%
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Abacavir hydroxyacetate
Catalog No. T1267LCas No. 1446418-48-9
Abacavir hydroxyacetate is an orally active nucleoside analog reverse transcriptase inhibitor. It has anti-HIV and immunomodulatory activity, induces arterial thrombosis in a mouse model, and can be used to study HIV infection.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $149 | 7-10 days |
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CitedProduct Introduction
Bioactivity
Chemical Properties
| Description | Abacavir hydroxyacetate is an orally active nucleoside analog reverse transcriptase inhibitor. It has anti-HIV and immunomodulatory activity, induces arterial thrombosis in a mouse model, and can be used to study HIV infection. |
| In vivo | In 6 to 8-week-old male and female SCID mice with implantation of psoriatic tissue, Abacavir hydroxyacetate (10 and 20 mg/kg; oral gavage; 10-20 mg/kg once) decreases the concentration of PRINS and IL-20, and reduces the lesion area of the skin, showing a better effect than methotrexate in controlling psoriasis[1]. |
| Alias | Abacavirhydroxyacetate |
| Molecular Weight | 344.37 |
| Formula | C16H20N6O3 |
| Cas No. | 1446418-48-9 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (232.31 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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