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BMS-986365

BMS-986365
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Purity:99.96%
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BMS-986365

Catalog No. T84297Cas No. 2446928-30-7
BMS-986365 (CC-94676) is an orally available, selective and highly potent AR degrader with potential anticancer activity that inhibits AR signaling and suppresses tumor growth for the study of prostate cancer.
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Pack SizePriceAvailabilityQuantity
1 mg$193In Stock
5 mg$486In Stock
10 mg$778In Stock
25 mg$1,550In Stock
50 mg$2,480In Stock
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Product Introduction

Bioactivity
Description
BMS-986365 (CC-94676) is an orally available, selective and highly potent AR degrader with potential anticancer activity that inhibits AR signaling and suppresses tumor growth for the study of prostate cancer.
AliasCC-94676
Chemical Properties
Molecular Weight818.91
FormulaC41H45F3N8O5S
Cas No.2446928-30-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (97.69 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2211 mL6.1057 mL12.2114 mL61.0568 mL
5 mM0.2442 mL1.2211 mL2.4423 mL12.2114 mL
10 mM0.1221 mL0.6106 mL1.2211 mL6.1057 mL
20 mM0.0611 mL0.3053 mL0.6106 mL3.0528 mL
50 mM0.0244 mL0.1221 mL0.2442 mL1.2211 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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