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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $98 | In Stock | |
5 mg | $233 | In Stock | |
10 mg | $378 | In Stock | |
25 mg | $635 | In Stock | |
50 mg | $885 | In Stock | |
100 mg | $1,230 | In Stock | |
1 mL x 10 mM (in DMSO) | $261 | In Stock |
Description | Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib is an effective and orally active Bruton tyrosine kinase inhibitor (IC50: 1 nM). Remibrutinib has the potential for Chronic urticaria (CU) treatment. |
In vitro | Remibrutinib inhibits Btk enzymatic activity (IC50: 1 nM in a biochemical enzyme assay). Remibrutinib inhibits Btk enzymatic activity in the blood (IC50: 0.023 μM in vitro B cell activation assay), the whole blood is collected from the abdominal aorta of anesthetized adult male Lewis rats[1]. |
Molecular Weight | 507.53 |
Formula | C27H27F2N5O3 |
Cas No. | 1787294-07-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 125 mg/mL (246.29 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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