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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $107 | In Stock | |
2 mg | $157 | In Stock | |
5 mg | $263 | In Stock | |
10 mg | $428 | In Stock | |
25 mg | $885 | In Stock | |
50 mg | $1,450 | In Stock | |
100 mg | $1,980 | In Stock | |
200 mg | $2,770 | In Stock | |
1 mL x 10 mM (in DMSO) | $297 | In Stock |
Description | BTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. BTRX-335140 can distribute well into the CNS. ADMET (absorption, distribution, metabolism, excretion, and toxicity) . BTRX-335140 endows with favorable in vitro ADMET and in vivo pharmacokinetic profiles and medication-like duration of action in rats. |
Targets&IC50 | κ opioid receptor:0.8 nM, δ opioid receptor:6500 nM, μ opioid receptor:110 nM |
Alias | CYM-53093 |
Molecular Weight | 453.55 |
Formula | C25H32FN5O2 |
Cas No. | 2244614-14-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 5.5 mg/mL (12.13 mM), Sonication is recommended. ![]() | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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