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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $73 | In Stock | |
5 mg | $158 | In Stock | |
10 mg | $286 | In Stock | |
25 mg | $485 | In Stock | |
50 mg | Inquiry | In Stock | |
1 mL x 10 mM (in DMSO) | $242 | In Stock |
Description | MK-8353 (SCH900353) is a potent, selective and orally available inhibitor of ERK1/2 (IC50s of 23.0 nM and 8.8 nM, respectively) |
In vitro | MK-8353 is a potent, selective and orally available inhibitor of ERK1/2 (IC50s of 23.0 nM and 8.8 nM, respectively); MK-8353 has antitumor activity. |
In vivo | MK-8353 causes at least 50% tumor growth inhibition or regression in 83% of the animal models bearing different tumor cells[1]. |
Alias | SCH900353 |
Molecular Weight | 691.84 |
Formula | C37H41N9O3S |
Cas No. | 1184173-73-6 |
Storage | store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 125 mg/mL (180.68 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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