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SCD1 inhibitor-4

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Catalog No. T10525Cas No. 1295541-87-5

SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.

SCD1 inhibitor-4

SCD1 inhibitor-4

🥰Excellent
Purity: 99.71%
Catalog No. T10525Cas No. 1295541-87-5
SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.
Pack SizePriceAvailabilityQuantity
2 mg$38In Stock
5 mg$58In Stock
10 mg$106In Stock
25 mg$213In Stock
50 mg$343In Stock
100 mg$493In Stock
200 mg$685In Stock
1 mL x 10 mM (in DMSO)$68In Stock
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Purity:99.71%
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Product Introduction

Bioactivity
Description
SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.
In vivo
SCD1 inhibitor-4 (1~30 mg/kg) demonstrates a dose-dependent decrease in the desaturation index, with a 55% reduction at 1 mg/kg and an 85% reduction at 10 and 30 mg/kg doses[1].
Chemical Properties
Molecular Weight363.34
FormulaC17H16F3N5O
Cas No.1295541-87-5
SmilesCc1c(ncn1Cc1cccc(c1)C(F)(F)F)C(=O)Nc1ccn(C)n1
Relative Density.1.36 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 90 mg/mL (247.70 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7522 mL13.7612 mL27.5224 mL137.6122 mL
5 mM0.5504 mL2.7522 mL5.5045 mL27.5224 mL
10 mM0.2752 mL1.3761 mL2.7522 mL13.7612 mL
20 mM0.1376 mL0.6881 mL1.3761 mL6.8806 mL
50 mM0.0550 mL0.2752 mL0.5504 mL2.7522 mL
100 mM0.0275 mL0.1376 mL0.2752 mL1.3761 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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