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AR 231453

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Purity:99.45%

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COA HPLC HNMR

AR 231453

Catalog No. T8329Cas No. 733750-99-7

AR 231453 is a selective and orally available GPR119 agonist,can stimulate β-cell replication and improve islet graft function.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$30	In Stock
5 mg	$63	In Stock
10 mg	$97	In Stock
25 mg	$158	In Stock
50 mg	$228	In Stock
100 mg	$355	In Stock
1 mL x 10 mM (in DMSO)	$72	In Stock

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Product Introduction

Bioactivity

Description

AR 231453 is a selective and orally available GPR119 agonist,can stimulate β-cell replication and improve islet graft function.

Chemical Properties

Molecular Weight	505.52
Formula	C21H24FN7O5S
Cas No.	733750-99-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mg/mL (19.78 mM), Sonication is recommended.

H2O: 60 mg/mL (118.69 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	1.9782 mL	9.8908 mL	19.7816 mL	98.9081 mL
5 mM	0.3956 mL	1.9782 mL	3.9563 mL	19.7816 mL
10 mM	0.1978 mL	0.9891 mL	1.9782 mL	9.8908 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.0989 mL	0.4945 mL	0.9891 mL	4.9454 mL
50 mM	0.0396 mL	0.1978 mL	0.3956 mL	1.9782 mL
100 mM	0.0198 mL	0.0989 mL	0.1978 mL	0.9891 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc