Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMU-212, a methylated form of Resveratrol, shows antimitotic, antiproliferative, and antioxidant activities. DMU-212 induces mitotic arrest through the activation of ERK1/2 protein and the promotion of apoptosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 30.00 | |
5 mg | In stock | $ 48.00 | |
10 mg | In stock | $ 80.00 | |
25 mg | In stock | $ 163.00 | |
50 mg | In stock | $ 288.00 | |
100 mg | In stock | $ 428.00 | |
500 mg | In stock | $ 969.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 54.00 |
Description | DMU-212, a methylated form of Resveratrol, shows antimitotic, antiproliferative, and antioxidant activities. DMU-212 induces mitotic arrest through the activation of ERK1/2 protein and the promotion of apoptosis. |
Targets&IC50 | Proliferation:0.5 μM(A375), Proliferation:0.5 μM(Bro), Proliferation:1.25 μM(M5 human melanoma cells), Proliferation:1.25 μM(MeWo) |
In vitro | DMU-212 (0.3125-40 μM) inhibited the cellular proliferation of human melanoma cells at submicromolar or micromolar concentrations (IC50=0.5 μM, 0.5 μM, 1.25 μM, and 1.25 μM for A375, Bro, MeWo, and M5 human melanoma cells, respectively.)[2]. |
In vivo | In SCID female mice, DMU-212 (50 mg/kg; i.g.) inhibited tumor growth and lowered tumor burden[2]. |
Molecular Weight | 300.35 |
Formula | C18H20O4 |
CAS No. | 134029-62-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/mL (66.59 mM)
You can also refer to dose conversion for different animals. More
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DMU-212 134029-62-2 Apoptosis MAPK ERK DMU212 Inhibitor antimitotic Resveratrol antioxidant DMU 212 inhibit Extracellular signal regulated kinases anticancer inhibitor