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MK-8325
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MK-8325
Catalog No. T24480Cas No. 1334314-19-0
MK-8325 is a potent and orally available HCV NS5A inhibitor with replicative activity against a wide range of genotypes.MK-8325 has demonstrated bioavailability in in vitro and in vivo assays and has a favorable overall ADME profile.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $380 | In Stock | |
| 5 mg | $890 | In Stock | |
| 10 mg | $1,230 | In Stock | |
| 25 mg | $1,830 | In Stock | |
| 50 mg | $2,480 | In Stock | |
| 100 mg | $3,350 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $1,590 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | MK-8325 is a potent and orally available HCV NS5A inhibitor with replicative activity against a wide range of genotypes.MK-8325 has demonstrated bioavailability in in vitro and in vivo assays and has a favorable overall ADME profile. |
| In vitro | MK-8325 (7 μM) demonstrates no cell toxicity with a CC50 > 25 mM against Huh-7 replicon cells in a standard MTS assay.[1] |
| In vivo | In vivo assays showed MK-8325 to be orally bioavailable with pharmacokinetics suitable for once-daily dosing in patients and good overall ADME profiles.[1] |
| Alias | MK 8325, MK8325 |
| Molecular Weight | 915.93 |
| Formula | C43H54Cl2F2N8O6Si |
| Cas No. | 1334314-19-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||
| Solubility Information | DMSO: 9.16 mg/mL (10 mM)  | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Dose Conversion
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