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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $81 | In Stock | |
2 mg | $128 | In Stock | |
5 mg | $239 | In Stock | |
10 mg | $347 | In Stock | |
25 mg | $562 | In Stock | |
50 mg | $787 | In Stock | |
100 mg | $1,090 | In Stock | |
500 mg | $2,230 | In Stock | |
1 mL x 10 mM (in DMSO) | $263 | In Stock |
Description | SKLB-23bb is an orally bioavailable HDAC6-selective inhibitor and also has microtubule-disrupting ability. |
In vivo | In vivo efficacy evaluations of colorectal HCT116, acute myelocytic leukemia MV4-11, and B cell lymphoma Romas xenografts, SKLB-23bb more effectively inhibited the tumor growth than SAHA even at a 4-fold reduced dose or ACY-1215 at the same dose. SKLB-23bb is a potent oral anticancer candidate for selective HDAC6 inhibitor. |
Molecular Weight | 396.44 |
Formula | C21H24N4O4 |
Cas No. | 1815580-06-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 32 mg/mL (80.72 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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