Shopping Cart
- Remove All
- Your shopping cart is currently empty
GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nM
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $35 | In Stock | |
5 mg | $85 | In Stock | |
10 mg | $139 | In Stock | |
25 mg | $227 | In Stock | |
50 mg | $328 | In Stock | |
100 mg | $496 | In Stock | |
1 mL x 10 mM (in DMSO) | $88 | In Stock |
Description | GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nM |
Targets&IC50 | RET:0.4 nM |
In vitro | The effect of GSK3179106 on human and rat RET enzymatic activity and motesanib on human RET enzymatic activity was determined in an in vitro biochemical homogeneous time-resolved fluorescence (HTRF) assay. |
In vivo | GSK3179106 (3 or 10 mg/kg; orally; BID for 3.5 days) reduces the visceromotor response (VMR) compared to rats administered an acetic acid enema and treated with a vehicle. |
Molecular Weight | 467.41 |
Formula | C22H21F4N3O4 |
Cas No. | 1627856-64-7 |
Smiles | CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2cc(on2)C(C)(C)C(F)(F)F)c(F)c1 |
Relative Density. | 1.37 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (213.94 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.