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Estetrol

Catalog No. T15248Cas No. 15183-37-6
Alias Donesta

Estetrol(Donesta) is an orally available, selective modulator of the estrogen receptor, a naturally occurring estrogen synthesized by the human fetal liver during pregnancy.Estetrol has effects on the endometrium or central nervous system, but is antagonistic to the breast.Estetrol may help to reduce thrombosis at low concentrations. Estetrol may be used to relieve menopausal symptoms.

Estetrol

Estetrol

Purity: 99.83%
Catalog No. T15248Alias DonestaCas No. 15183-37-6
Estetrol(Donesta) is an orally available, selective modulator of the estrogen receptor, a naturally occurring estrogen synthesized by the human fetal liver during pregnancy.Estetrol has effects on the endometrium or central nervous system, but is antagonistic to the breast.Estetrol may help to reduce thrombosis at low concentrations. Estetrol may be used to relieve menopausal symptoms.
Pack SizePriceAvailabilityQuantity
1 mg$128In Stock
5 mg$326In Stock
10 mg$486In Stock
25 mg$778In Stock
50 mg$1,060In Stock
100 mg$1,430In Stock
1 mL x 10 mM (in DMSO)$443In Stock
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Purity:99.83%
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Product Introduction

Bioactivity
Description
Estetrol(Donesta) is an orally available, selective modulator of the estrogen receptor, a naturally occurring estrogen synthesized by the human fetal liver during pregnancy.Estetrol has effects on the endometrium or central nervous system, but is antagonistic to the breast.Estetrol may help to reduce thrombosis at low concentrations. Estetrol may be used to relieve menopausal symptoms.
AliasDonesta
Chemical Properties
Molecular Weight304.38
FormulaC18H24O4
Cas No.15183-37-6
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 90 mg/mL (295.68 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2854 mL16.4268 mL32.8537 mL164.2683 mL
5 mM0.6571 mL3.2854 mL6.5707 mL32.8537 mL
10 mM0.3285 mL1.6427 mL3.2854 mL16.4268 mL
20 mM0.1643 mL0.8213 mL1.6427 mL8.2134 mL
50 mM0.0657 mL0.3285 mL0.6571 mL3.2854 mL
100 mM0.0329 mL0.1643 mL0.3285 mL1.6427 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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