Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $226 | In Stock | |
2 mg | $337 | In Stock | |
5 mg | $562 | In Stock | |
10 mg | $892 | In Stock | |
25 mg | $1,990 | In Stock | |
50 mg | $3,270 | In Stock | |
100 mg | $5,200 | In Stock |
Description | Iclepertin (BI-425809) is an orally active and selective inhibitor of glycine transporter protein 1 (GlyT1).Iclepertin is used for the treatment of central nervous system disorders such as Alzheimer;s disease. Iclepertin is used for central nervous system disorders such as Alzheimer;s disease, schizophrenia and cognitive disorders. |
In vitro | As an inhibitor of GlyT1, Iclepertin has IC50 values of 5.2 nM and 5.0 nM in primary rat neurons and human SK-N-MC cells, respectively[1]. |
In vivo | In rats, oral administration of Iclepertin (BI 425809) induces a dose-dependent increase in cerebrospinal fluid levels of glycine from 30% (0.2 mg/kg) to 78% (2 mg/kg)[1]. |
Alias | BI-425809 |
Molecular Weight | 512.42 |
Formula | C20H18F6N2O5S |
Cas No. | 1421936-85-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.