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ALX-1393
🥰Excellent
Catalog No. T14198Cas No. 949164-09-4
ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits the activity of spontaneous networks by inducing glycinergic tetanic currents in the abdominal horn of the spinal cord. Antiinjurious effects on thermal, mechanical and chemical stimuli in rat models of acute pain.
ALX-1393
🥰Excellent
Purity: 99.73%
Catalog No. T14198Cas No. 949164-09-4
ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits the activity of spontaneous networks by inducing glycinergic tetanic currents in the abdominal horn of the spinal cord. Antiinjurious effects on thermal, mechanical and chemical stimuli in rat models of acute pain.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $1,380 | In Stock | |
| 5 mg | $2,800 | In Stock | |
| 10 mg | $3,780 | In Stock | |
| 25 mg | $5,620 | In Stock | |
| 50 mg | $7,590 | In Stock | |
| 100 mg | $9,870 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $2,880 | In Stock |
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Purity:99.73%
ee:95.26%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits the activity of spontaneous networks by inducing glycinergic tetanic currents in the abdominal horn of the spinal cord. Antiinjurious effects on thermal, mechanical and chemical stimuli in rat models of acute pain. |
| In vivo | ALX1393 (i.c.v.; 25, 50, and 100 μg) suppresses the late-phase response in the formalin test in normal rats without affecting motor performance and demonstrates dose-dependent inhibition of mechanical and cold hyperalgesia. [1] |
| Molecular Weight | 395.42 |
| Formula | C23H22FNO4 |
| Cas No. | 949164-09-4 |
| Smiles | C(OC[C@@H](C(O)=O)N)(C1=C(OCC2=CC=CC=C2)C=CC=C1)C3=CC(F)=CC=C3 |
| Relative Density. | 1.263 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 11 mg/mL (27.82 mM)  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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