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ALX-1393
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ALX-1393
Catalog No. T14198Cas No. 949164-09-4
ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits the activity of spontaneous networks by inducing glycinergic tetanic currents in the abdominal horn of the spinal cord. Antiinjurious effects on thermal, mechanical and chemical stimuli in rat models of acute pain.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $1,380 | In Stock | |
| 5 mg | $2,800 | In Stock | |
| 10 mg | $3,780 | In Stock | |
| 25 mg | $5,620 | In Stock | |
| 50 mg | $7,590 | In Stock | |
| 100 mg | $9,870 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $2,880 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits the activity of spontaneous networks by inducing glycinergic tetanic currents in the abdominal horn of the spinal cord. Antiinjurious effects on thermal, mechanical and chemical stimuli in rat models of acute pain. |
| In vivo | ALX1393 (i.c.v.; 25, 50, and 100 μg) suppresses the late-phase response in the formalin test in normal rats while having no impact on motor performance. Additionally, ALX1393 exhibits dose-dependent inhibition of mechanical and cold hyperalgesia. [1] |
| Molecular Weight | 395.42 |
| Formula | C23H22FNO4 |
| Cas No. | 949164-09-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||
| Solubility Information | DMSO: 11 mg/mL (27.82 mM)  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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