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Methoxyamine HCl (Methoxyamine) covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis. Methoxyamine is an orally bioavailable small molecule inhibitor with potential adjuvant activity. This agent may potentiate the anti-tumor activity of alkylating agents.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 g | $35 | In Stock | |
1 mL x 10 mM (in DMSO) | $29 | In Stock |
Description | Methoxyamine HCl (Methoxyamine) covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis. Methoxyamine is an orally bioavailable small molecule inhibitor with potential adjuvant activity. This agent may potentiate the anti-tumor activity of alkylating agents. |
Alias | TRC-102, TRC102, TRC 102, Methoxyamine |
Molecular Weight | 83.51 |
Formula | CH6ClNO |
Cas No. | 593-56-6 |
Smiles | Cl.CON |
Relative Density. | 0.854g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: Soluble DMSO: 55 mg/ml (658.6 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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