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Deferasirox (Fe3+ chelate)
🥰Excellent
Catalog No. T13639Cas No. 554435-83-5
Deferasirox (Fe3+ chelate) is an orally available iron chelator with potential anticancer activity, inhibits the anti-apoptotic activity of MCL-1, and can be used to study iron overload.
Deferasirox (Fe3+ chelate)
🥰Excellent
Catalog No. T13639Cas No. 554435-83-5
Deferasirox (Fe3+ chelate) is an orally available iron chelator with potential anticancer activity, inhibits the anti-apoptotic activity of MCL-1, and can be used to study iron overload.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $159 | In Stock |
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Purity:≥98.0%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Deferasirox (Fe3+ chelate) is an orally available iron chelator with potential anticancer activity, inhibits the anti-apoptotic activity of MCL-1, and can be used to study iron overload. |
| In vitro | Deferasirox (Fe3+ chelate) promotes cell cycle arrest in cervical cancer cell lines by regulating the expression of cell cycle regulatory factors cyclin D1, cyclin E, and proliferating cell nuclear antigen (PCNA)[1]. |
| Molecular Weight | 426.18 |
| Formula | C21H12FeN3O4 |
| Cas No. | 554435-83-5 |
| Smiles | O=C([O-])C1=CC=C(C=C1)N2N=C3C=4C=CC=CC4[O-][Fe+3]5[O-]C=6C=CC=CC6C2=[N]35 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 30 mg/mL (70.39 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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