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Enavogliflozin
Catalog No. T38843Cas No. 1415472-28-4
Alias DWP-16001
Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor.
Enavogliflozin
Catalog No. T38843Alias DWP-16001Cas No. 1415472-28-4
Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $158 | In Stock | |
| 5 mg | $397 | In Stock | |
| 10 mg | $622 | In Stock | |
| 25 mg | $1,080 | In Stock | |
| 50 mg | $1,480 | In Stock | |
| 100 mg | $1,960 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $437 | In Stock |
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View MoreInhibitors Related to "Enavogliflozin"
Empagliflozin
Cited
BI 10773
T1766864070-44-0
Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6. Empagliflozin is used for the treatment of type 2 diabetes.
- $39
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CitedCanagliflozin Cited
TA 7284, JNJ 28431754AAA, JNJ 28431754, JNJ 24831754ZAE
T1782842133-18-0
Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor that inhibits CHO cells expressing mSGLT2, rSGLT2, and hSGLT2 (IC50=2/3.7/4.4 nM). Canagliflozin can be used for the treatment of type II diabetes mellitus (T2DM).
- $43
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CitedPhloretin
RJC 02792, NSC 407292, Dihydronaringenin
T292460-82-2
Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leaves and the Manchurian apricot. It promotes potent antioxidative activities in peroxynitrite scavenging and the inhibition of lipid peroxidation. It has been found to inhibit the growth of several cancer cells and induce apoptosis of B16 melanoma and HL60 human leukemia cells.
- $46
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Canagliflozin hemihydrate
TA-7284, TA7284, TA 7284, JNJ-28431754, JNJ28431754, JNJ 28431754
T1782L928672-86-0
Canagliflozin hemihydrate (TA 7284) is a drug of the gliflozin class or subtype 2 sodium-glucose transport inhibitors used for the treatment of type 2 diabetes. SGLT2 is responsible for at least 90% of renal glucose reabsorption (SGLT1 being responsible for the remaining 10%). Blocking this transporter causes up to 119 grams of blood glucose per day to be eliminated through the urine, corresponding to 476 kilocalories.
- $49
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Phlorizin Cited
Phloridzin, NSC 2833, Floridzin
T292260-81-1
Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .
- $46
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CitedDapagliflozin ((2S)-1,2-propanediol, hydrate)
Dapagliflozin propanediol monohydrate, BMS-512148 (2S)-1,2-propanediol, hydrate
T4460960404-48-2
Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2), in development for treating type 2 diabetes mellitus (T2DM). It inhibits SGLT2, responsible for at least 90% of glucose reabsorption in the kidney.
- $37
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Dapagliflozin Cited
BMS-512148
T2389461432-26-8
Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.
- $42
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CitedErtugliflozin
PF-04971729, MK-8835
T49991210344-57-2
PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).
- $45
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Ipragliflozin
ASP1941
T2385761423-87-4
Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.
- $52
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Ertugliflozin L-pyroglutamic acid
PF-04971729 L-pyroglutamic acid
T152441210344-83-4
Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM, suitable for studies on the treatment of type 2 diabetes mellitus.
- $39
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Sergliflozin A
T68174360775-96-8In house
Sergliflozin A is a selective SGLT2 inhibitor that induces diabetes in a dose-dependent manner. It reduces hyperglycemia.
- $112
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Tofogliflozin (hydrate)
Tofogliflozin hydrate, CSG-452 hydrate
T50161201913-82-7
Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2, with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2, respectively.
- $38
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Purity:97.81%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor. |
| In vitro | Enavogliflozin (DWP-16001), a best-in-class antidiabetic agent, functions as a selective and orally active sodium-glucose cotransporter-2 (SGLT-2) inhibitor, as supported by references [1][2][3]. |
| Alias | DWP-16001 |
| Molecular Weight | 446.92 |
| Formula | C24H27ClO6 |
| Cas No. | 1415472-28-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (223.75 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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