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Aleplasinin

Aleplasinin
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Purity:97.51%
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Aleplasinin

Catalog No. T29856Cas No. 481629-87-2
Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic system. Aleplasinin can be used in Alzheimer's disease studies.
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Pack SizePriceAvailabilityQuantity
1 mg$52In Stock
5 mg$123In Stock
10 mg$198In Stock
25 mg$455In Stock
50 mg$689In Stock
100 mg$1,090In Stock
1 mL x 10 mM (in DMSO)$148In Stock
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Product Introduction

Bioactivity
Description
Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic system. Aleplasinin can be used in Alzheimer's disease studies.
AliasPAZ 417, PAZ417, PAZ-417
Chemical Properties
Molecular Weight425.52
FormulaC28H27NO3
Cas No.481629-87-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 245 mg/mL (575.77 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3501 mL11.7503 mL23.5007 mL117.5033 mL
5 mM0.4700 mL2.3501 mL4.7001 mL23.5007 mL
10 mM0.2350 mL1.1750 mL2.3501 mL11.7503 mL
20 mM0.1175 mL0.5875 mL1.1750 mL5.8752 mL
50 mM0.0470 mL0.2350 mL0.4700 mL2.3501 mL
100 mM0.0235 mL0.1175 mL0.2350 mL1.1750 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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