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Loureirin B

🥰Excellent
Catalog No. T3876Cas No. 119425-90-0

Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved.

Loureirin B

Loureirin B

🥰Excellent
Purity: 99.86%
Catalog No. T3876Cas No. 119425-90-0
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved.
Pack SizePriceAvailabilityQuantity
1 mg$48In Stock
5 mg$123In Stock
10 mg$179In Stock
25 mg$297In Stock
50 mg$453In Stock
100 mg$653In Stock
1 mL x 10 mM (in DMSO)$135In Stock
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Purity:99.86%
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Product Introduction

Bioactivity
Description
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved.
Targets&IC50
PAI1:26.10 μM
Chemical Properties
Molecular Weight316.35
FormulaC18H20O5
Cas No.119425-90-0
SmilesCOc1cc(OC)c(CCC(=O)c2ccc(O)cc2)c(OC)c1
Relative Density.1.177 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 150 mg/mL (474.16 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1611 mL15.8053 mL31.6106 mL158.0528 mL
5 mM0.6322 mL3.1611 mL6.3221 mL31.6106 mL
10 mM0.3161 mL1.5805 mL3.1611 mL15.8053 mL
20 mM0.1581 mL0.7903 mL1.5805 mL7.9026 mL
50 mM0.0632 mL0.3161 mL0.6322 mL3.1611 mL
100 mM0.0316 mL0.1581 mL0.3161 mL1.5805 mL

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