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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $72 | In Stock | |
10 mg | $98 | In Stock | |
25 mg | $169 | In Stock | |
50 mg | $248 | In Stock | |
100 mg | $368 | In Stock | |
1 mL x 10 mM (in DMSO) | $79 | In Stock |
Description | Ispronicline (TC-1734) An orally active, selective, and potent α4β2 nAChR partial agonist with antidepressant, neuroprotective, and long-lasting cognitive effects.Ispronicline has a high affinity for the α4β2 nAChR with a Ki= 11 nM. |
In vivo | In rats, the subcutaneous administration of Ispronicline (10-20 mg/kg) leads to the induction of c-Fos expression in specific regions of the forebrain[1]. The pharmacokinetics of Ispronicline, characterized by a half-life of 2 hours in rats, contrasts with the sustained enhancement of working memory, lasting from 18 hours to 2 days[2]. |
Alias | AZD-3480, RJR-1734, AZD 3480, TC 1734, AZD3480, TC-01734, TC-1734-112 |
Molecular Weight | 234.34 |
Formula | C14H22N2O |
Cas No. | 252870-53-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (213.37 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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