Shopping Cart

Remove All

Your shopping cart is currently empty

NEO2734

Select Batch

Purity:100%

Resource Download

COA HNMR HPLC

NEO2734

Catalog No. T8658Cas No. 2081072-29-7

NEO2734 (EP31670) is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$116	In Stock
5 mg	$289	In Stock
10 mg	$478	In Stock
25 mg	$789	In Stock
50 mg	$1,080	In Stock
100 mg	$1,480	In Stock
500 mg	$2,970	In Stock
1 mL x 10 mM (in DMSO)	$318	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "NEO2734"

Product Introduction

Bioactivity

Description	NEO2734 (EP31670) is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).
In vitro	NEO2734, a novel dual inhibitor of BET and CBP/p300, is active in both hotspot mutant (F133V) and non-hotspot mutant (Q165P) PCa cells in vitro and in vivo[1].
Alias	EP31670

Chemical Properties

Molecular Weight	435.44
Formula	C22H24F3N3O3
Cas No.	2081072-29-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 27.5 mg/mL (63.15 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2965 mL	11.4826 mL	22.9653 mL	114.8264 mL
5 mM	0.4593 mL	2.2965 mL	4.5931 mL	22.9653 mL
10 mM	0.2297 mL	1.1483 mL	2.2965 mL	11.4826 mL
20 mM	0.1148 mL	0.5741 mL	1.1483 mL	5.7413 mL
50 mM	0.0459 mL	0.2297 mL	0.4593 mL	2.2965 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc