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K-111 (BM-170744) is an orally available peroxisome proliferator-activated receptor (PPAR)-alpha agonist and insulin enhancer for the study of obesity-type diabetes mellitus and the metabolic syndrome.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $293 | In Stock | |
5 mg | $722 | In Stock | |
10 mg | $987 | In Stock | |
25 mg | $1,520 | In Stock | |
50 mg | $1,980 | In Stock |
Description | K-111 (BM-170744) is an orally available peroxisome proliferator-activated receptor (PPAR)-alpha agonist and insulin enhancer for the study of obesity-type diabetes mellitus and the metabolic syndrome. |
In vivo | K-111 treatment (chronic doses: 1, 3 and 10 mg/kg/d per 3 doses for 4 weeks) resulted in significant weight loss, improvement in hyperinsulinemia, insulin sensitivity, hypertriglyceridemia, and HDL cholesterol levels, and no significant effects on fasting glucose, 24-hour urinary excretion, systolic or diastolic blood pressure, plasma fibrinogen, total cholesterol, or chemical and hematological profile significant effect. [6] |
Alias | K111, K 111, BM-170744, BM170744, BM 170744 |
Molecular Weight | 379.75 |
Formula | C18H25Cl3O2 |
Cas No. | 221564-97-2 |
Smiles | O=C(O)C(Cl)(Cl)CCCCCCCCCCC1=CC=C(Cl)C=C1 |
Relative Density. | 1.199 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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