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TFEB activator 1

🥰Excellent
Catalog No. T8055Cas No. 39777-61-2
Alias RPN77612, Curcumin analog compound C1, Curcumin analog C1, (1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,

TFEB activator 1 (Curcumin analog compound C1) is an activator of transcription factor EB (TFEB) with promise for the prevention or treatment of Alzheimer's disease.

TFEB activator 1

TFEB activator 1

🥰Excellent
Purity: 99.77%
Catalog No. T8055Alias RPN77612, Curcumin analog compound C1, Curcumin analog C1, (1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,Cas No. 39777-61-2
TFEB activator 1 (Curcumin analog compound C1) is an activator of transcription factor EB (TFEB) with promise for the prevention or treatment of Alzheimer's disease.
Pack SizePriceAvailabilityQuantity
2 mg$35In Stock
5 mg$57In Stock
10 mg$85In Stock
25 mg$166In Stock
50 mg$288In Stock
100 mg$450In Stock
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Purity:99.77%
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Product Introduction

Bioactivity
Description
TFEB activator 1 (Curcumin analog compound C1) is an activator of transcription factor EB (TFEB) with promise for the prevention or treatment of Alzheimer's disease.
Targets&IC50
Flag-TFEB nuclear translocation:2167 nM (EC50)
AliasRPN77612, Curcumin analog compound C1, Curcumin analog C1, (1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,
Chemical Properties
Molecular Weight294.34
FormulaC19H18O3
Cas No.39777-61-2
SmilesCOc1ccccc1\C=C\C(=O)\C=C\c1ccccc1OC
Relative Density.1.128 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 59 mg/mL (200.45 mM)
Ethanol: 2 mg/mL (6.79 mM)
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM3.3974 mL16.9872 mL33.9743 mL169.8716 mL
5 mM0.6795 mL3.3974 mL6.7949 mL33.9743 mL
DMSO
1mg5mg10mg50mg
10 mM0.3397 mL1.6987 mL3.3974 mL16.9872 mL
20 mM0.1699 mL0.8494 mL1.6987 mL8.4936 mL
50 mM0.0679 mL0.3397 mL0.6795 mL3.3974 mL
100 mM0.0340 mL0.1699 mL0.3397 mL1.6987 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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