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NP-G2-044

🥰Excellent
Catalog No. T9107Cas No. 1807454-59-6

NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.

NP-G2-044

NP-G2-044

🥰Excellent
Purity: 99.66%
Catalog No. T9107Cas No. 1807454-59-6
NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.
Pack SizePriceAvailabilityQuantity
1 mg$48 In Stock
2 mg$68 In Stock
5 mg$101 In Stock
10 mg$150 In Stock
25 mg$312 In Stock
50 mg$473 In Stock
100 mg$693 In Stock
500 mg$1,460 In Stock
1 mL x 10 mM (in DMSO)$118 In Stock
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Purity:99.66%
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Product Introduction

Bioactivity
Description
NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.
Targets&IC50
Fascin:2 μM
In vitro
NP-G2-044 inhibits the migration of MDA-MB-231 tumor cells with an IC50 of approximately 10 μM, reducing filopodial and subsequently lamellipodial formation[1].
In vivo
NP-G2-044 (100 mg/kg; i.p.; daily for 18 days) inhibits breast tumor metastasis in mouse models[1].
Chemical Properties
Molecular Weight399.37
FormulaC21H16F3N3O2
Cas No.1807454-59-6
SmilesCc1occc1C(=O)Nc1nn(Cc2ccc(cc2)C(F)(F)F)c2ccccc12
Relative Density.1.36 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (250.39 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5039 mL12.5197 mL25.0394 mL125.1972 mL
5 mM0.5008 mL2.5039 mL5.0079 mL25.0394 mL
10 mM0.2504 mL1.2520 mL2.5039 mL12.5197 mL
20 mM0.1252 mL0.6260 mL1.2520 mL6.2599 mL
50 mM0.0501 mL0.2504 mL0.5008 mL2.5039 mL
100 mM0.0250 mL0.1252 mL0.2504 mL1.2520 mL

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