Shopping Cart
- Remove All
- Your shopping cart is currently empty
NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $48 | In Stock | |
2 mg | $68 | In Stock | |
5 mg | $101 | In Stock | |
10 mg | $150 | In Stock | |
25 mg | $312 | In Stock | |
50 mg | $473 | In Stock | |
100 mg | $693 | In Stock | |
500 mg | $1,460 | In Stock | |
1 mL x 10 mM (in DMSO) | $118 | In Stock |
Description | NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response. |
Targets&IC50 | Fascin:2 μM |
In vitro | NP-G2-044 inhibits the migration of MDA-MB-231 tumor cells with an IC50 of approximately 10 μM, reducing filopodial and subsequently lamellipodial formation[1]. |
In vivo | NP-G2-044 (100 mg/kg; i.p.; daily for 18 days) inhibits breast tumor metastasis in mouse models[1]. |
Molecular Weight | 399.37 |
Formula | C21H16F3N3O2 |
Cas No. | 1807454-59-6 |
Smiles | Cc1occc1C(=O)Nc1nn(Cc2ccc(cc2)C(F)(F)F)c2ccccc12 |
Relative Density. | 1.36 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (250.39 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.