Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Cefoxitin

😃Good
Catalog No. T20643Cas No. 35607-66-0
Alias Rephoxitin, Cefoxitinum

Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls. Its activity profile includes Gram-negative and Gram-positive bacteria, and is commonly used in abdominal cavity infections, pelvic infections, and certain types of gynecological infections, and is highly effective against anaerobic bacteria.

Cefoxitin

Cefoxitin

😃Good
Purity: 99.8%
Catalog No. T20643Alias Rephoxitin, CefoxitinumCas No. 35607-66-0
Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls. Its activity profile includes Gram-negative and Gram-positive bacteria, and is commonly used in abdominal cavity infections, pelvic infections, and certain types of gynecological infections, and is highly effective against anaerobic bacteria.
Pack SizePriceAvailabilityQuantity
500 mg$967-10 days
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "Cefoxitin"

Select Batch
Purity:99.8%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls. Its activity profile includes Gram-negative and Gram-positive bacteria, and is commonly used in abdominal cavity infections, pelvic infections, and certain types of gynecological infections, and is highly effective against anaerobic bacteria.
Targets&IC50
PBP2a:0.72 μg/mL, PBP5:0.19 μg/mL, PBP3:1.04 μg/mL, PBP2b:0.19 μg/mL, PBP4:0.14 μg/mL
In vitro
Cefoxitin demonstrates effective antimicrobial properties against Gram-positive bacteria, with minimum inhibitory concentrations (MICs) spanning from 1-6 μg/mL for various Gram-positive pathogens[1]. Furthermore, at a concentration of 1.25 µM/mL, Cefoxitin exhibits potent bactericidal activity against B. burgdorferi[2].
In vivo
Cefoxitin administration at a dose of 20 mg/kg via intraperitoneal injection for 5 consecutive days demonstrates effective eradication of B. burgdorferi in the C3H/HeN mouse model.[2]
AliasRephoxitin, Cefoxitinum
Chemical Properties
Molecular Weight427.45
FormulaC16H17N3O7S2
Cas No.35607-66-0
Smiles[H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@]2(NC(=O)Cc1cccs1)OC)C(O)=O
Relative Density.1.63 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 90.0 mg/mL (210.6 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3395 mL11.6973 mL23.3945 mL116.9727 mL
5 mM0.4679 mL2.3395 mL4.6789 mL23.3945 mL
10 mM0.2339 mL1.1697 mL2.3395 mL11.6973 mL
20 mM0.1170 mL0.5849 mL1.1697 mL5.8486 mL
50 mM0.0468 mL0.2339 mL0.4679 mL2.3395 mL
100 mM0.0234 mL0.1170 mL0.2339 mL1.1697 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Cefoxitin | purchase Cefoxitin | Cefoxitin cost | order Cefoxitin | Cefoxitin chemical structure | Cefoxitin in vivo | Cefoxitin in vitro | Cefoxitin formula | Cefoxitin molecular weight