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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $299 | Backorder |
Description | Nemonoxacin (TG-873870) is an orally available non-fluorinated quinolone antibiotic with broad-spectrum antimicrobial activity against staphylococci, streptococci, and enterococci, as well as against Neisseria gonorrhoeae and Haemophilus influenzae.Nemonoxacin is used in the study of bacterial infections and community-acquired pneumonia. |
In vitro | Nemonoxacin (0-5.51 µM; 24 hours) inhibits both methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) with MIC90 values of 0.12 µg/mL and 4 µg/mL, respectively[1]. |
In vivo | In CD-1 ICR mice (18-22 g; mouse systemic infection model), Nemonoxacin (1.6-4.0 mg/kg; oral administration; 15 minutes and 6 hours after infection) exhibited antibacterial activity against various resistant Staphylococcus aureus infections[2]. |
Alias | TG-873870 |
Molecular Weight | 371.43 |
Formula | C20H25N3O4 |
Cas No. | 378746-64-6 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
Solubility Information | DMSO: 1 mg/mL (2.69 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
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