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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $31 | In Stock | |
5 mg | $72 | In Stock | |
10 mg | $122 | In Stock | |
25 mg | $263 | In Stock | |
50 mg | $447 | In Stock | |
100 mg | $659 | In Stock | |
1 mL x 10 mM (in DMSO) | $79 | In Stock |
Description | NCB-0846 is an orally active TNIK inhibitor (IC50: 21 nM). |
In vivo | Sixty normal male and female volunteers between 18 and 40 years of age were recruited for a double-masked, placebo-controlled, crossover study in which each eye of each subject was dilated with 2.5% phenylephrine. After one hour, one eye was treated with 0.5% dapiprazole, and the contralateral eye was treated with placebo. |
Alias | NCB 0846 |
Molecular Weight | 375.42 |
Formula | C21H21N5O2 |
Cas No. | 1792999-26-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (133.18 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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