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Butibufen
Butibufen (FF-106) is an orally active non-steroidal anti-inflammatory compound, a potential cyclooxygenase inhibitor with analgesic and antipyretic activity, and inhibits urea synthesis.Butibufen has been used in the study of rheumatic diseases.
Catalog No. T26926Cas No. 55837-18-8
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Purity:99.29%
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Butibufen
Catalog No. T26926Cas No. 55837-18-8
Butibufen (FF-106) is an orally active non-steroidal anti-inflammatory compound, a potential cyclooxygenase inhibitor with analgesic and antipyretic activity, and inhibits urea synthesis.Butibufen has been used in the study of rheumatic diseases.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $35 | In Stock | |
| 5 mg | $76 | In Stock | |
| 10 mg | $109 | In Stock | |
| 25 mg | $179 | In Stock | |
| 50 mg | $267 | In Stock | |
| 100 mg | $396 | In Stock | |
| 500 mg | $942 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Butibufen (FF-106) is an orally active non-steroidal anti-inflammatory compound, a potential cyclooxygenase inhibitor with analgesic and antipyretic activity, and inhibits urea synthesis.Butibufen has been used in the study of rheumatic diseases. |
| In vitro | In hepatocytes from Sprague-Dawley male rats, Butibufen (0.1 μM-0.1 M; 60 min) exhibited no cell viability effects at a dose of 200 μM, but dose- and time-dependently affected cell viability at higher concentrations[2]. |
| In vivo | In Sprague-Dawley rats, Butibufen (50 and 250 mg/kg; oral gavage) reduces acid phosphatase activity but does not affect the stability of lysosomal membranes[3]. |
| Alias | FF 105, FF-106, FF 106, FF106 |
| Molecular Weight | 220.31 |
| Formula | C14H20O2 |
| Cas No. | 55837-18-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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