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Lenampicillin hydrochloride
Catalog No. T15734Cas No. 80734-02-7
Alias KBT 1585 hydrochloride
Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skin and soft tissue infection.
Lenampicillin hydrochloride
Catalog No. T15734Alias KBT 1585 hydrochlorideCas No. 80734-02-7
Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skin and soft tissue infection.
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Product Introduction
Bioactivity
Chemical Properties
| Description | Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skin |
| In vivo | Lenampicillin hydrochloride (LAPC) is identified for its main metabolites in rats and dogs. The main metabolite in peripheral plasma is 2,3-butanediol in rats and dogs, On the other hand, high levels of acetoin are found in portal plasma for an early period after the dosing of LAPC. These results show that the biotransformation of propriety in LAPC to acetoin carried out mainly in intestinal tissues, but acetoin is converted to 2,3-butanediol in the liver[3]. Lenampicillin hydrochloride (p.o.; 0-1000 mg/kg) does not cause death in dogs, and the maximum dose of in this acute toxicity study is recorded because of causing emesis[2]. |
| Alias | KBT 1585 hydrochloride |
| Molecular Weight | 497.95 |
| Formula | C21H24ClN3O7S |
| Cas No. | 80734-02-7 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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