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Tubulin inhibitor 32
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Tubulin inhibitor 32
Catalog No. T78701Cas No. 2923531-39-7
Tubulin inhibitor 32 is an orally active novel microtubule inhibitor with antiproliferative and antitumor activity, inhibits microtubule polymerization, induces apoptosis and cell cycle arrest in G2/M phase.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $293 | In Stock | |
| 5 mg | $722 | In Stock | |
| 10 mg | $987 | In Stock | |
| 25 mg | $1,520 | In Stock | |
| 50 mg | $1,980 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Tubulin inhibitor 32 is an orally active novel microtubule inhibitor with antiproliferative and antitumor activity, inhibits microtubule polymerization, induces apoptosis and cell cycle arrest in G2/M phase. |
| In vitro | In HepG2, SW480, Hela, and MDA-MB-231 cells, Tubulin inhibitor 32 (0-64 µM; 48 hours) exhibited anti-proliferative activity, with IC50 values of 1.54, 37.53, 24.61, and 11.41 µM, respectively[1]. |
| In vivo | In 4-6 weeks old male nude mice (HCT-116 tumor model), Tubulin inhibitor 32 (50, 100 mg/kg; oral administration; once daily for 20 days) decreased the tumor volume and tumor weight by 44.1% and 27.0%, respectively[1]. |
| Molecular Weight | 325.36 |
| Formula | C18H19N3O3 |
| Cas No. | 2923531-39-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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