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Nastorazepide

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Catalog No. TQ0062Cas No. 209219-38-5
Alias Z-360

Nastorazepide (Z-360) is a selective, orally available antagonist of the gastrin/cholecystokinin 2 (CCK-2) receptor with potential antineoplastic activity.

Nastorazepide

Nastorazepide

🥰Excellent
Purity: 99.60%
Catalog No. TQ0062Alias Z-360Cas No. 209219-38-5
Nastorazepide (Z-360) is a selective, orally available antagonist of the gastrin/cholecystokinin 2 (CCK-2) receptor with potential antineoplastic activity.
Pack SizePriceAvailabilityQuantity
1 mg$48In Stock
5 mg$97In Stock
10 mg$189In Stock
25 mg$363In Stock
50 mg$553In Stock
100 mg$798In Stock
1 mL x 10 mM (in DMSO)$123In Stock
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Purity:99.60%
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Product Introduction

Bioactivity
Description
Nastorazepide (Z-360) is a selective, orally available antagonist of the gastrin/cholecystokinin 2 (CCK-2) receptor with potential antineoplastic activity.
In vitro
Nastorazepide binds to the gastrin/CCK-2 receptor, thereby preventing receptor activation by gastrin, a peptide hormone frequently associated with the proliferation of gastrointestinal and pancreatic tumor cells[1].
In vivo
Nastorazepide significantly inhibits the growth of subcutaneous xenografts of human pancreatic tumor cells in mice, and that Nastorazepide combined with gemcitabine prolonged survival in a pancreatic carcinoma orthotopic xenograft mice[1].
AliasZ-360
Chemical Properties
Molecular Weight520.62
FormulaC29H36N4O5
Cas No.209219-38-5
SmilesCC(C)(C)C(=O)CN1c2ccccc2N(C[C@@H](NC(=O)Nc2cccc(c2)C(O)=O)C1=O)C1CCCCC1
Relative Density.1.29 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 30 mg/mL (57.63 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9208 mL9.6039 mL19.2079 mL96.0393 mL
5 mM0.3842 mL1.9208 mL3.8416 mL19.2079 mL
10 mM0.1921 mL0.9604 mL1.9208 mL9.6039 mL
20 mM0.0960 mL0.4802 mL0.9604 mL4.8020 mL
50 mM0.0384 mL0.1921 mL0.3842 mL1.9208 mL

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