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Nastorazepide
Catalog No. TQ0062Cas No. 209219-38-5
Alias Z-360
Nastorazepide (Z-360) is a selective, orally available antagonist of the gastrin/cholecystokinin 2 (CCK-2) receptor with potential antineoplastic activity.
Nastorazepide
Catalog No. TQ0062Alias Z-360Cas No. 209219-38-5
Nastorazepide (Z-360) is a selective, orally available antagonist of the gastrin/cholecystokinin 2 (CCK-2) receptor with potential antineoplastic activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $48 | In Stock | |
| 5 mg | $97 | In Stock | |
| 10 mg | $189 | In Stock | |
| 25 mg | $363 | In Stock | |
| 50 mg | $553 | In Stock | |
| 100 mg | $798 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $123 | In Stock |
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Purity:99.60%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Nastorazepide (Z-360) is a selective, orally available antagonist of the gastrin/cholecystokinin 2 (CCK-2) receptor with potential antineoplastic activity. |
| In vitro | Nastorazepide binds to the gastrin/CCK-2 receptor, thereby preventing receptor activation by gastrin, a peptide hormone frequently associated with the proliferation of gastrointestinal and pancreatic tumor cells[1]. |
| In vivo | Nastorazepide significantly inhibits the growth of subcutaneous xenografts of human pancreatic tumor cells in mice, and that Nastorazepide combined with gemcitabine prolonged survival in a pancreatic carcinoma orthotopic xenograft mice[1]. |
| Alias | Z-360 |
| Molecular Weight | 520.62 |
| Formula | C29H36N4O5 |
| Cas No. | 209219-38-5 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 30 mg/mL (57.63 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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