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Enarodustat

Catalog No. T15219Cas No. 1262132-81-9
Alias JTZ-951

Enarodustat (JTZ-951) is an orally active factor inhibitor of prolyl hydroxylase (EC50: 0.22 μM) and has the potential for renal anemia treatment.

Enarodustat

Enarodustat

Purity: 99.61%
Catalog No. T15219Alias JTZ-951Cas No. 1262132-81-9
Enarodustat (JTZ-951) is an orally active factor inhibitor of prolyl hydroxylase (EC50: 0.22 μM) and has the potential for renal anemia treatment.
Pack SizePriceAvailabilityQuantity
1 mg$33In Stock
2 mg$46In Stock
5 mg$72In Stock
10 mg$117In Stock
25 mg$198In Stock
50 mg$328In Stock
100 mg$487In Stock
1 mL x 10 mM (in DMSO)$83In Stock
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Purity:99.61%
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Product Introduction

Bioactivity
Description
Enarodustat (JTZ-951) is an orally active factor inhibitor of prolyl hydroxylase (EC50: 0.22 μM) and has the potential for renal anemia treatment.
Targets&IC50
Factor prolyl hydroxylase:(EC50)0.22 μM
In vitro
Enarodustat exhibits neither CYP (IC50 > 100 μM; CYP3A4/5, CYP2C9, CYP2D6, CYP1A2, CYP2A6, CYP2C19, CYP2C8, CYP2B6) nor hERG (IC50 > 100 μM) inhibition.
In vivo
Enarodustat [1 and 3 mg/kg, p.o., in rats] treatment increases hemoglobin levels in a dose-dependent manner.
AliasJTZ-951
Chemical Properties
Molecular Weight340.33
FormulaC17H16N4O4
Cas No.1262132-81-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 83.33 mg/mL (244.85 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9383 mL14.6916 mL29.3832 mL146.9162 mL
5 mM0.5877 mL2.9383 mL5.8766 mL29.3832 mL
10 mM0.2938 mL1.4692 mL2.9383 mL14.6916 mL
20 mM0.1469 mL0.7346 mL1.4692 mL7.3458 mL
50 mM0.0588 mL0.2938 mL0.5877 mL2.9383 mL
100 mM0.0294 mL0.1469 mL0.2938 mL1.4692 mL

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