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JAK-IN-30
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Catalog No. T79235Cas No. 2891469-99-9
JAK-IN-30 (compound 31) is a water-soluble Janus kinase (JAK) inhibitor with IC50 values of 2 nM for JAK2, 15 nM for JAK1, 18 nM for JAK3, and 2 nM for TYK2, identified for its research potential in treating dry eye disease (DED) [1].
JAK-IN-30
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Catalog No. T79235Cas No. 2891469-99-9
JAK-IN-30 (compound 31) is a water-soluble Janus kinase (JAK) inhibitor with IC50 values of 2 nM for JAK2, 15 nM for JAK1, 18 nM for JAK3, and 2 nM for TYK2, identified for its research potential in treating dry eye disease (DED) [1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $125 | 35 days | |
| 5 mg | $490 | 35 days | |
| 10 mg | $875 | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | JAK-IN-30 (compound 31) is a water-soluble Janus kinase (JAK) inhibitor with IC50 values of 2 nM for JAK2, 15 nM for JAK1, 18 nM for JAK3, and 2 nM for TYK2, identified for its research potential in treating dry eye disease (DED) [1]. |
| Targets&IC50 | JAK1:15 nM, JAK2:2 nM, JAK3:18 nM, TYK2:2 nM |
| Molecular Weight | 398.53 |
| Formula | C19H26N8S |
| Cas No. | 2891469-99-9 |
Storage & Solubility Information
| Storage | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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