α-L-Fucopyranos

Name: α-L-Fucopyranos
Brand: TargetMol
SKU: T203819
Rating: 4.5 (1 reviews)

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Catalog No. T203819Cas No. 6696-41-9

Alias α-L-Fucose, Deoxy-a-L-galactopyranose, Alpha-L-Fucose, Alpha-L-Fucopyranose

α-L-fucopyranose, an endogenous metabolite and six-carbon deoxyhexose, is present at the terminal or anterior position of many cell surface oligosaccharide ligands, mediates cell recognition and adhesion signaling pathways, and is a potentially critical molecule in pathological processes, including tumors.

α-L-Fucopyranos

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Catalog No. T203819Alias α-L-Fucose, Deoxy-a-L-galactopyranose, Alpha-L-Fucose, Alpha-L-FucopyranoseCas No. 6696-41-9

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Product Introduction

Bioactivity

Description	α-L-fucopyranose, an endogenous metabolite and six-carbon deoxyhexose, is present at the terminal or anterior position of many cell surface oligosaccharide ligands, mediates cell recognition and adhesion signaling pathways, and is a potentially critical molecule in pathological processes, including tumors.
In vitro	Methods: RAW264.7 macrophages were treated with α-L-Fucopyranos (5 mg/ml, 10 mg/ml, 4 hours), and the cells were collected to quantify the levels of IL-6 and MCP-1 by qPCR. Results: Quantitative PCR Results showed that the levels of Mcp1 and Il6 decreased in a concentration-dependent manner in RAW264.7 cells (Figure 5C), indicating that α-L-Fucopyranos can alleviate inflammation in vivo and in vitro. [2]
In vivo	Methods: α-L-Fucopyranos (100 mg/kg, intraperitoneal injection, three times a week) was used to treat HuCCT-1 cell-transplanted tumor model mice, and tumor volume and body weight were measured daily. Results: Tumor size, angiogenesis, and stiffness index were reduced in the α-L-Fucopyranos-treated group, indicating that α-L-Fucopyranos can inhibit tumor growth in mice. [3]
Alias	α-L-Fucose, Deoxy-a-L-galactopyranose, Alpha-L-Fucose, Alpha-L-Fucopyranose

Chemical Properties

Molecular Weight	164.16
Formula	C₆H₁₂O₅
Cas No.	6696-41-9
Smiles	O[C@H]1[C@@H](O)[C@H](O)[C@H](O)O[C@H]1C

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store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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