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Product Introduction

Bioactivity

Description	L-Xylose (L-(-)-Xylose), a levo-isomer of Xylose, is classified as an aldopentose-type monosaccharide.
In vitro	The permeability characteristics of L-xylose have been compared in isolated intact rat diaphragm muscle preparations, in the absence and presence of exogenous insulin. In the absence of added insulin, L-xylose distributed in less than a third of the total cell water. In the presence of added insulin, intracellular distribution of L-xylose is increased. L-Xylose distributed in 50 per cent of the intracellular water. A significant lag period was observed before the insulin effect upon the penetration of L-xylose was evident. The lag period with L-xylose could be abolished by pretreating the tissues with insulin for 1 hour[2].
Alias	L-(-)-Xylose

Chemical Properties

Molecular Weight	150.13
Formula	C₅H₁₀O₅
Cas No.	609-06-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 70 mg/mL (466.26 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.6609 mL	33.3045 mL	66.6089 mL	333.0447 mL
5 mM	1.3322 mL	6.6609 mL	13.3218 mL	66.6089 mL
10 mM	0.6661 mL	3.3304 mL	6.6609 mL	33.3045 mL
20 mM	0.3330 mL	1.6652 mL	3.3304 mL	16.6522 mL
50 mM	0.1332 mL	0.6661 mL	1.3322 mL	6.6609 mL
100 mM	0.0666 mL	0.3330 mL	0.6661 mL	3.3304 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

XyloseL XyloseL-Xyloselevo-isomerInhibitorinhibitLXylose