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LDN-27219

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Catalog No. T11831Cas No. 312946-37-5

LDN-27219 is a potent hTGase inhibitor with IC50 of 0.6 uM.

LDN-27219

LDN-27219

😃Good
Purity: 99.38%
Catalog No. T11831Cas No. 312946-37-5
LDN-27219 is a potent hTGase inhibitor with IC50 of 0.6 uM.
Pack SizePriceAvailabilityQuantity
1 mg$33In Stock
5 mg$76In Stock
10 mg$123In Stock
25 mg$263In Stock
50 mg$495In Stock
100 mg$758In Stock
500 mg$1,530Backorder
1 mL x 10 mM (in DMSO)$84In Stock
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Purity:99.38%
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Product Introduction

Bioactivity
Description
LDN-27219 is a potent hTGase inhibitor with IC50 of 0.6 uM.
Targets&IC50
TGase (human):0.6 uM
Chemical Properties
Molecular Weight408.5
FormulaC20H16N4O2S2
Cas No.312946-37-5
SmilesNNC(=O)CSc1nc2scc(-c3ccccc3)c2c(=O)n1-c1ccccc1
Relative Density.1.45 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (244.8 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4480 mL12.2399 mL24.4798 mL122.3990 mL
5 mM0.4896 mL2.4480 mL4.8960 mL24.4798 mL
10 mM0.2448 mL1.2240 mL2.4480 mL12.2399 mL
20 mM0.1224 mL0.6120 mL1.2240 mL6.1200 mL
50 mM0.0490 mL0.2448 mL0.4896 mL2.4480 mL
100 mM0.0245 mL0.1224 mL0.2448 mL1.2240 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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