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LDN-27219

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Purity:99.38%

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COA HNMR HPLC

LDN-27219

Catalog No. T11831Cas No. 312946-37-5

LDN-27219 is a potent hTGase inhibitor with IC50 of 0.6 uM.

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Pack Size	Price	Availability
1 mg	$33	In Stock
5 mg	$76	In Stock
10 mg	$123	In Stock
25 mg	$263	In Stock
50 mg	$495	In Stock
100 mg	$758	In Stock
500 mg	$1,530	Backorder
1 mL x 10 mM (in DMSO)	$84	In Stock

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Product Introduction

Bioactivity

Description

LDN-27219 is a potent hTGase inhibitor with IC50 of 0.6 uM.

Chemical Properties

Molecular Weight	408.5
Formula	C20H16N4O2S2
Cas No.	312946-37-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 100 mg/mL (244.8 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4480 mL	12.2399 mL	24.4798 mL	122.3990 mL
5 mM	0.4896 mL	2.4480 mL	4.8960 mL	24.4798 mL
10 mM	0.2448 mL	1.2240 mL	2.4480 mL	12.2399 mL
20 mM	0.1224 mL	0.6120 mL	1.2240 mL	6.1200 mL
50 mM	0.0490 mL	0.2448 mL	0.4896 mL	2.4480 mL
100 mM	0.0245 mL	0.1224 mL	0.2448 mL	1.2240 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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