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MAHMA NONOate is a pH-dependent NO donor.MAHMA NONOate inhibits collagen or ADP-induced platelet aggregation.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $30 | In Stock |
Description | MAHMA NONOate is a pH-dependent NO donor.MAHMA NONOate inhibits collagen or ADP-induced platelet aggregation. |
In vitro | MAHMA NONOate (0.1 nM - 100 μM) induces concentration-dependent inhibition of collagen or ADP-induced platelet aggregation, but its potency as an aggregation inhibitor is inferior to its potency as a pulmonary vasodilator [1]. |
In vivo | Intravenous injection of MAHMA NONOate (0.3-10 nmol/kg/min; once) in pentobarbital-anesthetized male Wistar rats led to dose-dependent decreases in mean systemic arterial pressure, proving more effective than GSNO, and also caused dose-dependent inhibition of the response to 0.3 μM/kg ADP[2]. |
Molecular Weight | 204.27 |
Formula | C8H20N4O2 |
Cas No. | 146724-86-9 |
Storage | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: 40 mg/mL (195.82 mM), when pH is adjusted to 10 with NaOH. Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
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