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Mc-Gly-Gly-Phe-Gly-PAB-OH TFA

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Catalog No. T77833
Alias Mc-GGFG-PAB-OH TFA

Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs).

Mc-Gly-Gly-Phe-Gly-PAB-OH TFA

Mc-Gly-Gly-Phe-Gly-PAB-OH TFA

😃Good
Catalog No. T77833Alias Mc-GGFG-PAB-OH TFA
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs).
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Product Introduction

Bioactivity
Description
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs).
In vitro
ADC comprises an antibody to which a cytotoxic agent is linked via an ADC connector.
AliasMc-GGFG-PAB-OH TFA
Chemical Properties
Molecular Weight748.7
FormulaC34H39F3N6O10
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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