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Mesaconic acid

Mesaconic acid (Methylfumaric acid) is used as a fire retardant, as recent studies revealed this acid is a competitive inhibitor of fumarate reduction.

Catalog No. T20880Cas No. 498-24-8

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Purity:99.68%

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Mesaconic acid

Catalog No. T20880Cas No. 498-24-8

Mesaconic acid (Methylfumaric acid) is used as a fire retardant, as recent studies revealed this acid is a competitive inhibitor of fumarate reduction.

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Pack Size	Price	Availability
5 mg	$29	In Stock
10 mg	$45	In Stock
25 mg	$77	In Stock
50 mg	$115	In Stock
100 mg	$172	In Stock
200 mg	$255	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Product Introduction

Bioactivity

Description	Mesaconic acid (Methylfumaric acid) is used as a fire retardant, as recent studies revealed this acid is a competitive inhibitor of fumarate reduction.
Alias	Methylfumaric acid, Mesaconate, Kyselina mesakonova

Chemical Properties

Molecular Weight	130.1
Formula	C₅H₆O₄
Cas No.	498-24-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 55 mg/ml (422.75 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	7.6864 mL	38.4320 mL	76.8640 mL	384.3198 mL
5 mM	1.5373 mL	7.6864 mL	15.3728 mL	76.8640 mL
10 mM	0.7686 mL	3.8432 mL	7.6864 mL	38.4320 mL
20 mM	0.3843 mL	1.9216 mL	3.8432 mL	19.2160 mL
50 mM	0.1537 mL	0.7686 mL	1.5373 mL	7.6864 mL
100 mM	0.0769 mL	0.3843 mL	0.7686 mL	3.8432 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Mesaconic acid