Shopping Cart
- Remove All
Your shopping cart is currently empty
Methyl methanesulfonate
🥰Excellent
Catalog No. T9985Cas No. 66-27-3
Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders.
Methyl methanesulfonate
🥰Excellent
Catalog No. T9985Cas No. 66-27-3
Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 g | $29 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Methyl methanesulfonate"
Busulfan
Sulphabutin, Myleran, Busulphan
T092355-98-1
Busulfan (Busulphan) is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation of DNA. Following systemic absorption of busulfan, carbonium ions are formed, resulting in DNA alkylation and DNA breaks and inhibition of DNA replication and RNA transcription.
- $45
Size
QTY
Streptozocin
Cited
U 9889, STZ, Streptozotocin, NSC-85998
T150718883-66-4
Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation. Streptozocin is toxic to insulin-producing pancreatic islet B-cells and is commonly used in the construction of animal models of type 1 diabetes. The product is unstable in solution and is recommended to be dispensed now.
- $30
Size
QTY
CitedLomustine
NSC 79037, CCNU
T160113010-47-4
Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.
- $50
Size
QTY
Altretamine
WR-95704, RB-1515, NSC13875, Hexamethylmelamine, ENT-50852
T1241645-05-6
Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity.
- $30
Size
QTY
Thio-TEPA
Triethylenethiophosphoramide, Tiofosyl, Tiofosfamid
T125052-24-4
Thio-TEPA (Tiofosyl) is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
- $31
Size
QTY
Chlorambucil
WR-139013, Chloroambucil, CB-1348
T0975305-03-3
Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis.
- $50
Size
QTY
O6-Benzylguanine Cited
T753919916-73-5
O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.
- $42
Size
QTY
CitedTreosulfan
Treosulphan, NSC 39069
T17159299-75-2
Treosulfan (NSC 39069) is a bifunctional alkylating agent used in the treatment of advanced ovarian cancer.[2]
- $33
Size
QTY
Carmustine Cited
Nitrumon, Gliadel, Carmubris, bis-chloroethylnitrosourea, BiCNU, BCNU
T3091154-93-8
Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent.
- $40
Size
QTY
CitedLomeguatrib
PaTrin-2
T2495192441-08-0
Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .
- $43
Size
QTY
DN-1289
T73457In house
DN-1289 is an orally available, blood-brain barrier-crossing, selective and potent inhibitor with an IC50 value of 17 nM for di-leucine zipper kinase (DLK) and 40 nM for leucine zipper-bearing kinase (LZK).DN-1289 significantly inhibited optic nerve crush (ONC)-induced p-c-Jun in a mouse model.
- $350
Size
QTY
VAL-083
Dianhydrogalactitol, Dianhydrodulcitol
T1721223261-20-3
VAL-083 is an alkylating agent with antitumor activity that produces N7 methylation on DNA.
- $48
Size
QTY
Select Batch
Purity:≥98%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders. |
| Molecular Weight | 110.13 |
| Formula | C2H6O3S |
| Cas No. | 66-27-3 |
| Smiles | COS(C)(=O)=O |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (544.81 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Methyl methanesulfonate | purchase Methyl methanesulfonate | Methyl methanesulfonate cost | order Methyl methanesulfonate | Methyl methanesulfonate chemical structure | Methyl methanesulfonate formula | Methyl methanesulfonate molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.