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ML-178

🥰Excellent
Catalog No. T22102Cas No. 1355026-47-9
Alias CYM50179

ML-178, a dichlorobenzene, is a potent and selective agonist of sphingosine-1-phosphate receptor 4 (S1PR4), with an EC50 of 46 nM, and has no effect on other S1P receptors at a concentration of 25 μM.

ML-178

ML-178

🥰Excellent
Purity: 95.92%
Catalog No. T22102Alias CYM50179Cas No. 1355026-47-9
ML-178, a dichlorobenzene, is a potent and selective agonist of sphingosine-1-phosphate receptor 4 (S1PR4), with an EC50 of 46 nM, and has no effect on other S1P receptors at a concentration of 25 μM.
Pack SizePriceAvailabilityQuantity
2 mg$42 In Stock
5 mg$67 In Stock
10 mg$117 In Stock
25 mg$247 In Stock
50 mg$422 In Stock
100 mg$628 In Stock
1 mL x 10 mM (in DMSO)$75 In Stock
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Purity:95.92%
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Product Introduction

Bioactivity
Description
ML-178, a dichlorobenzene, is a potent and selective agonist of sphingosine-1-phosphate receptor 4 (S1PR4), with an EC50 of 46 nM, and has no effect on other S1P receptors at a concentration of 25 μM.
AliasCYM50179
Chemical Properties
Molecular Weight441.93
FormulaC13H9Br2Cl2NO2
Cas No.1355026-47-9
SmilesClc1ccc(OCCOc2ccc(Br)nc2Br)c(Cl)c1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 15 mg/mL (33.94 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2628 mL11.3140 mL22.6280 mL113.1401 mL
5 mM0.4526 mL2.2628 mL4.5256 mL22.6280 mL
10 mM0.2263 mL1.1314 mL2.2628 mL11.3140 mL
20 mM0.1131 mL0.5657 mL1.1314 mL5.6570 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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