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ML204 hydrochloride

Catalog No. T24481Cas No. 2070015-10-8
Alias ML204 HCl, ML-204, ML204

ML204 is a potent inhibitor of the TRPC4 channel. ML204 inhibited TRPC4β-mediated intracellular Ca(2+) rise (IC50: 0.96 μM) and exhibited 19-fold selectivity against muscarinic receptor-coupled TRPC6 channel activation.

ML204 hydrochloride
Other Forms of ML204 hydrochloride:
ML204T22985465-86-1
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ML204 hydrochloride

Catalog No. T24481Alias ML204 HCl, ML-204, ML204Cas No. 2070015-10-8
ML204 is a potent inhibitor of the TRPC4 channel. ML204 inhibited TRPC4β-mediated intracellular Ca(2+) rise (IC50: 0.96 μM) and exhibited 19-fold selectivity against muscarinic receptor-coupled TRPC6 channel activation.
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2 mg$495 days
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Product Introduction

Bioactivity
Description
ML204 is a potent inhibitor of the TRPC4 channel. ML204 inhibited TRPC4β-mediated intracellular Ca(2+) rise (IC50: 0.96 μM) and exhibited 19-fold selectivity against muscarinic receptor-coupled TRPC6 channel activation.
AliasML204 HCl, ML-204, ML204
Chemical Properties
Molecular Weight262.78
FormulaC15H19ClN2
Cas No.2070015-10-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

ML204 hydrochlorideML 204 HydrochlorideML204 HydrochlorideML-204 HydrochlorideML-204 hydrochlorideML 204
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