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mTOR inhibitor 9a

🥰Excellent
Catalog No. T67705Cas No. 1144075-32-0

mTOR inhibitor 9a inhibited the growth of human LNCap cells with an ic50 of 80 nm. 1-methyl-3 -{4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl}urea may have antitumor activity.

mTOR inhibitor 9a

mTOR inhibitor 9a

🥰Excellent
Purity: 99.75%
Catalog No. T67705Cas No. 1144075-32-0
mTOR inhibitor 9a inhibited the growth of human LNCap cells with an ic50 of 80 nm. 1-methyl-3 -{4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl}urea may have antitumor activity.
Pack SizePriceAvailabilityQuantity
1 mg$350In Stock
5 mg$828In Stock
10 mg$1,130In Stock
25 mg$1,590In Stock
50 mg$1,980In Stock
100 mg$2,500In Stock
500 mg$4,900In Stock
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Purity:99.75%
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Product Introduction

Bioactivity
Description
mTOR inhibitor 9a inhibited the growth of human LNCap cells with an ic50 of 80 nm. 1-methyl-3 -{4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl}urea may have antitumor activity.
Targets&IC50
PIK3CA:0.423 µM
Chemical Properties
Molecular Weight395.48
FormulaC20H21N5O2S
Cas No.1144075-32-0
SmilesN(C(NC)=O)C1=CC=C(C2=NC(=C3C(=N2)C=CS3)N4CC5OC(C4)CC5)C=C1
Relative Density.1.380 g/cm3 at 20℃ (Predicted)
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 12 mg/mL (30.34 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5286 mL12.6429 mL25.2857 mL126.4286 mL
5 mM0.5057 mL2.5286 mL5.0571 mL25.2857 mL
10 mM0.2529 mL1.2643 mL2.5286 mL12.6429 mL
20 mM0.1264 mL0.6321 mL1.2643 mL6.3214 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

mTOR inhibitor 9a1methyl3{4[4(8oxa3azabicyclo[3.2.1]oct3yl)thieno[3,2d]pyrimidin2yl]phenyl}urea
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