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N-deacetylated BMS-202

Catalog No. T12143Cas No. 2310135-18-1

N-deacetylated BMS-202 is the deacetylated of BMS-202.

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Pack Size	Price	Availability
2 mg	$62	5 days
5 mg	$130	5 days
1 mL x 10 mM (in DMSO)	$128	5 days

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Product Introduction

Bioactivity

Description	N-deacetylated BMS-202 is the deacetylated of BMS-202.
In vitro	N-deacetylated BMS-202 disrupts the interaction between PD-1 and PD-L1, potentially enhancing the immune response against various types of tumors. Using antibodies to target PD-L1 and block its binding with PD-1 has proven effective in reactivating and enhancing T cell activation across multiple systems [1].

Chemical Properties

Molecular Weight	377.48
Formula	C23H27N3O2
Cas No.	2310135-18-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 36 mg/mL (95.37 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6491 mL	13.2457 mL	26.4915 mL	132.4573 mL
5 mM	0.5298 mL	2.6491 mL	5.2983 mL	26.4915 mL
10 mM	0.2649 mL	1.3246 mL	2.6491 mL	13.2457 mL
20 mM	0.1325 mL	0.6623 mL	1.3246 mL	6.6229 mL
50 mM	0.0530 mL	0.2649 mL	0.5298 mL	2.6491 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc