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N3-C5-NHS ester

Name: N3-C5-NHS ester
Brand: TargetMol
SKU: T18468
Price: 47 EUR
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T18468Cas No. 866363-70-4

N3-C5-NHS ester, a noncleavable ADC linker, can be used in the synthesis of antibody-drug conjugates (ADCs).

N3-C5-NHS ester

🥰Excellent

Purity: 99.76%

Catalog No. T18468Cas No. 866363-70-4

N3-C5-NHS ester, a noncleavable ADC linker, can be used in the synthesis of antibody-drug conjugates (ADCs).

Pack Size	Price	Availability	Quantity
50 mg	50 €	In Stock
1 mL x 10 mM (in DMSO)	47 €	In Stock

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Purity:99.76%

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COA HPLC HNMR

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Product Introduction

Bioactivity

Description

N3-C5-NHS ester, a noncleavable ADC linker, can be used in the synthesis of antibody-drug conjugates (ADCs).

Chemical Properties

Molecular Weight	254.24
Formula	C₁₀H₁₄N₄O₄
Cas No.	866363-70-4
Smiles	O(C(CCCCCN=[N+]=[N-])=O)N1C(=O)CCC1=O
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 100 mg/mL (393.33 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9333 mL	19.6665 mL	39.3329 mL	196.6646 mL
5 mM	0.7867 mL	3.9333 mL	7.8666 mL	39.3329 mL
10 mM	0.3933 mL	1.9666 mL	3.9333 mL	19.6665 mL
20 mM	0.1967 mL	0.9833 mL	1.9666 mL	9.8332 mL
50 mM	0.0787 mL	0.3933 mL	0.7867 mL	3.9333 mL
100 mM	0.0393 mL	0.1967 mL	0.3933 mL	1.9666 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc