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Nardosinone

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Purity:99%

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COA HNMR HPLC

Nardosinone

Catalog No. T6S1740Cas No. 23720-80-1

1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed to OGD, which may be relevant to the promotion of PKA and ERK signaling pathway. 3. Nardosinone enhances staurosporine- or dbcAMP-induced neurite outgrowth from PC12D cells, probably by amplifying both the MAP kinase-dependent and -independent signaling pathways of dbcAMP and staurosporine. 4. The enhancement of NGF-induced neurite outgrowth from PC12D cells by Nardosinone involves activation of a down-stream step of the MAP kinase-dependent cascade of NGF coupled with PKC.

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Pack Size	Price	Availability
5 mg	$47	In Stock
10 mg	$80	In Stock
25 mg	$153	In Stock
50 mg	$248	In Stock
100 mg	$369	In Stock

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	250.33
Formula	C15H22O3
Cas No.	23720-80-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 46 mg/mL(183.8 mM)

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9947 mL	19.9736 mL	39.9473 mL	199.7363 mL
5 mM	0.7989 mL	3.9947 mL	7.9895 mL	39.9473 mL
10 mM	0.3995 mL	1.9974 mL	3.9947 mL	19.9736 mL
20 mM	0.1997 mL	0.9987 mL	1.9974 mL	9.9868 mL
50 mM	0.0799 mL	0.3995 mL	0.7989 mL	3.9947 mL
100 mM	0.0399 mL	0.1997 mL	0.3995 mL	1.9974 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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