Shopping Cart
- Remove All
Your shopping cart is currently empty
NMDAR antagonist 2
😃Good
Catalog No. T201550
NMDAR antagonist 2 (compound 3I) is a blood-brain barrier permeable antagonist of NMDA receptors, exhibiting IC50 values of 4.42 μM and 214.75 μM at membrane potentials of -60 mV and 40 mV, respectively, for hGluN1/hGluN2A. This compound has been shown to mitigate hippocampal damage.
NMDAR antagonist 2
NMDAR antagonist 2
😃Good
Catalog No. T201550
NMDAR antagonist 2 (compound 3I) is a blood-brain barrier permeable antagonist of NMDA receptors, exhibiting IC50 values of 4.42 μM and 214.75 μM at membrane potentials of -60 mV and 40 mV, respectively, for hGluN1/hGluN2A. This compound has been shown to mitigate hippocampal damage.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "NMDAR antagonist 2"
L-Glutamic acid
glutamic acid, glutacid, (S)-Glutamic acid, (+)-L-Glutamic acid
T2A249756-86-0
L-Glutamic acid (Glutaminol) acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.
- 39 €
Size
QTY
L-Phenylalanine
phenylalanine, 3-Phenyl-L-alanine, (S)-2-Amino-3-phenylpropionic acid
T337763-91-2
L-Phenylalanine (3-Phenyl-L-alanine) is an essential amino acid and the precursor of the amino acid tyrosine, acts as an antagonist at α2δ calcium channels.
- 28 €
Size
QTY
L-Glutamic acid monosodium salt
MSG, Monosodium glutamate, Glutavene, Glutacyl, Ajinomoto
T6871142-47-2
L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.
- 31 €
Size
QTY
glycine
Cited
Glycosthene, Glycolixir, Glycocoll, Aminoacetic acid, 2-Aminoacetic acid
T2O272856-40-6
glycine (2-Aminoacetic acid) is a non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
- 38 €
Size
QTY
CitedLinalool
Phantol, Linalol, (±)-Linalool
T2S226478-70-6
1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury through induction of antioxidant defense via Nrf2 activating and reduction inflammatory response via NF-κB inhibition. 3. Linalool biosynthesis and accumulation might be involved in plant defense against bacterial and fungal pathogens and be associated with field resistance to citrus canker. 4. Linalool significantly increased the expression of antioxidant enzymes regulated by Nrf-2 and diminished lung tissue levels of several pro-inflammatory cytokines, including tumor necrosis factor α (TNF-α) and interleukin (IL)-6.
- 27 €
Size
QTY
Mephenesin
Mephedan, Memphenesin, Decontractyl, Cresoxydiol
T001559-47-2
Mephenesin (Cresoxydiol) is a centrally acting muscle relaxant with a short duration of action.
- 31 €
Size
QTY
D-Cycloserine
RO-1-9213
T158968-41-7
D-Cycloserine (RO-1-9213) is a broad spectrum antibiotic used as a second line agent for treatment of drug resistant tuberculosis, always in combination with other antituberculosis agents.
- 40 €
Size
QTY
Piracetam
UCB-6215
T04267491-74-9
Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.
- 42 €
Size
QTY
Decanoic Acid
Decoic acid, Caprynic acid, CAPRIC ACID
T3379334-48-5
Decanoic Acid (Caprynic acid) acts as a non-competitive AMPA receptor antagonist.
- 39 €
Size
QTY
(-)-Aspartic acid
D-Aspartic acid, D-(-)-Aspartic acid, asparagic acid, Asp, Aminosuccinic acid
T48851783-96-6
(-)-Aspartic acid (L-Homoproline) is an endogenous amino acid existing in invertebrates and vertebrates. It can regulate testosterone synthesis and is an agonist of NMDA receptor.
- 38 €
Size
QTY
Memantine hydrochloride Cited
Namenda, Memantine HCl, D-145 (hydrochloride)
T144341100-52-1
Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparkinson agent.
- 39 €
Size
QTY
CitedQuinolinic acid
QUIN, pyridine-2,3-dicarboxylic acid
T409689-00-9
Quinolinic acid (QUIN) is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.
- 38 €
Size
QTY
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | NMDAR antagonist 2 (compound 3I) is a blood-brain barrier permeable antagonist of NMDA receptors, exhibiting IC50 values of 4.42 μM and 214.75 μM at membrane potentials of -60 mV and 40 mV, respectively, for hGluN1/hGluN2A. This compound has been shown to mitigate hippocampal damage. |
| Molecular Weight | 289.8 |
| Formula | C17H20ClNO |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy NMDAR antagonist 2 | purchase NMDAR antagonist 2 | NMDAR antagonist 2 cost | order NMDAR antagonist 2 | NMDAR antagonist 2 formula | NMDAR antagonist 2 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.