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Otamixaban
🥰Excellent
Catalog No. T16410Cas No. 193153-04-7
Alias XRP 0673, RPR 130673, FXV-673, FXV673, FXV 673
Otamixaban (FXV673) is a selective and highly effective Xa inhibitor that inhibits the generation of thrombin and can be used to study acute coronary syndrome.
Otamixaban
🥰Excellent
Purity: 98.08%
Catalog No. T16410Alias XRP 0673, RPR 130673, FXV-673, FXV673, FXV 673Cas No. 193153-04-7
Otamixaban (FXV673) is a selective and highly effective Xa inhibitor that inhibits the generation of thrombin and can be used to study acute coronary syndrome.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $299 | In Stock |
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Purity:98.08%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Otamixaban (FXV673) is a selective and highly effective Xa inhibitor that inhibits the generation of thrombin and can be used to study acute coronary syndrome. |
| Targets&IC50 | TMPRSS2:18.7 × 10 μM |
| In vitro | The HTS assay indicates that otamixaban shows inhibitory activity against TMPRSS2. IC50= 18.7 × 10 μM. Otamixaban in the Calu-3 cell line inhibits SARS-CoV-2 S-mediated viral entry. [5] |
| In vivo | Otamixaban is highly efficacious in rodent, canine and porcine models of thrombosis showed in vivo experiments. Recent clinical findings indicate that Otamixaban is efficacious, safe, and well-tolerated in humans and therefore has considerable potential for the treatment of acute coronary syndrome. |
| Alias | XRP 0673, RPR 130673, FXV-673, FXV673, FXV 673 |
| Molecular Weight | 446.5 |
| Formula | C25H26N4O4 |
| Cas No. | 193153-04-7 |
| Smiles | C(N[C@@H]([C@@H](CC1=CC(C(=N)N)=CC=C1)C(OC)=O)C)(=O)C2=CC=C(C=C2)C=3C=CN(=O)=CC3 |
| Relative Density. | 1.25 g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 40 mg/mL (89.59 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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